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1

Detection of drug specific circulating immune complexes from in vivo cynomolgus monkey serum samples

Pierog, Piotr, Krishna, Murli, Yamniuk, Aaron, Chauhan, Anil, DeSilva, Binodh

Journal:

Journal of Immunological Methods

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

2

Investigation of a Degradant in a Biologics Formulation Buffer Containing L-Histidine

Wang, Chunlei, Yamniuk, Aaron, Dai, Jun, Chen, Sike, Stetsko, Paul, Ditto, Noah, Zhang, Yingru

Journal:

Pharmaceutical Research

Year:

2015

Language:

english

File:

PDF, 801 KB

english, 2015

3

Isotope-labeled vibrational circular dichroism studies of calmodulin and its interactions with ligands

Aleksandra A. Pandyra, Aaron P. Yamniuk, Valery V. Andrushchenko, Helmut Wieser, Hans J. Vogel

Journal:

Year:

2005

Language:

english

File:

PDF, 221 KB

english, 2005

4

Auxiliary Ca2+ binding sites can influence the structure of CIB1

Aaron P. Yamniuk, Kathryn L. Anderson, Marie E. Fraser, Hans J. Vogel

Journal:

Protein Science

Year:

2009

Language:

english

File:

PDF, 462 KB

english, 2009

5

Calmodulin’s flexibility allows for promiscuity in its interactions with target proteins and peptides

Aaron P. Yamniuk, Hans J. Vogel

Journal:

Molecular Biotechnology

Year:

2004

Language:

english

File:

PDF, 670 KB

english, 2004

6

Protein conformational changes studied by diffusion NMR spectroscopy: Application to helix-loop-helix calcium binding proteins

Aalim M. Weljie, Aaron P. Yamniuk, Hidenori Yoshino, Yoshinobu Izumi, Hans J. Vogel

Journal:

Protein Science

Year:

2003

Language:

english

File:

PDF, 165 KB

english, 2003

7

Reversible and pH-dependent weak drug-excipient binding does not affect oral bioavailability of high dose drugs

Ajit S. Narang, Aaron P. Yamniuk, Limin Zhang, S. Nilgun Comezoglu, Dilbir S. Bindra, Sailesh Varia, Michael L. Doyle, Sherif Badawy

Journal:

Journal of Pharmacy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 766 KB

english, 2012

8

26-P: Increased sensitivity of HLA specificities assigned by luminex using a vacuum wash method compared to conventional washes

L. Hidalgo, C. Yamniuk, A. Halpin, P. Campbell

Journal:

Human Immunology

Year:

2009

Language:

english

File:

PDF, 87 KB

english, 2009

9

75-P: Comparison of HLA antibody detection between Luminex and flow cytometry

C. Yamniuk, L. Hidalgo, A. Halpin, P. Campbell

Journal:

Human Immunology

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

10

24-OR To proceed or not proceed? A single epitope reactivity with multiple strong Cw specificities yielding a negative crossmatch

Christine Yamniuk, Patricia Campbell, Anne Halpin, Luis Hidalgo

Journal:

Human Immunology

Year:

2011

Language:

english

File:

PDF, 196 KB

english, 2011

11

Thermodynamic characterization of the interactions between the immunoregulatory proteins osteopontin and lactoferrin

Aaron P. Yamniuk, Hans Burling, Hans J. Vogel

Journal:

Molecular Immunology

Year:

2009

Language:

english

File:

PDF, 835 KB

english, 2009

12

Thermodynamic Effects of Noncoded and Coded Methionine Substitutions in Calmodulin

Yamniuk, Aaron P., Ishida, Hiroaki, Lippert, Dustin, Vogel, Hans J.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 932 KB

english, 2009

13

Calcium- and magnesium-dependent interactions between calcium- and integrin-binding protein and the integrin αIIb cytoplasmic domain

Aaron P. Yamniuk, Hans J. Vogel

Journal:

Protein Science

Year:

2005

Language:

english

File:

PDF, 356 KB

english, 2005

14

Application of a kosmotrope-based solubility assay to multiple protein therapeutic classes indicates broad use as a high-throughput screen for protein therapeutic aggregation propensity

Yamniuk, Aaron P., Ditto, Noah, Patel, Mehul, Dai, Jun, Sejwal, Preeti, Stetsko, Paul, Doyle, Michael L.

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 1.29 MB

english, 2013

15

182-P

Yamniuk, Christine, Halpin, Anne, Campbell, Patricia, Hidalgo, Luis

Journal:

Human Immunology

Year:

2012

Language:

english

File:

PDF, 30 KB

english, 2012

16

Structural Investigation into the Differential Target Enzyme Regulation Displayed by Plant Calmodulin Isoforms †

Yamniuk, Aaron P., Vogel, Hans J.

Journal:

Year:

2005

Language:

english

File:

PDF, 185 KB

english, 2005

17

Metal Ion Binding Properties and Conformational States of Calcium- and Integrin-Binding Protein †

Yamniuk, Aaron P., Nguyen, Leonard T., Hoang, Tung T., Vogel, Hans J.

Journal:

Year:

2004

Language:

english

File:

PDF, 226 KB

english, 2004

18

Domain Stability and Metal-Induced Folding of Calcium- and Integrin-Binding Protein 1 †

Yamniuk, Aaron P., Silver, Dylan M., Anderson, Kathryn L., Martin, Stephen R., Vogel, Hans J.

Journal:

Year:

2007

Language:

english

File:

PDF, 375 KB

english, 2007

19

Effects of Metal-Binding Loop Mutations on Ligand Binding to Calcium- and Integrin-Binding Protein 1. Evolution of the EF-Hand? †

Yamniuk, Aaron P., Gifford, Jessica L., Linse, Sara, Vogel, Hans J.

Journal:

Year:

2008

Language:

english

File:

PDF, 603 KB

english, 2008

20

An Anti-CD154 Domain Antibody Prolongs Graft Survival and Induces Foxp3 + iTreg in the Absence and Presence of CTLA-4 Ig

Pinelli, D. F., Wagener, M. E., Liu, D., Yamniuk, A., Tamura, J., Grant, S., Larsen, C. P., Suri, A., Nadler, S. G., Ford, M. L.

Journal:

American Journal of Transplantation

Year:

2013

Language:

english

File:

PDF, 1.54 MB

english, 2013

21

Engineering of a Novel Anti-CD40L Domain Antibody for Treatment of Autoimmune Diseases

Xie, J. H., Yamniuk, A. P., Borowski, V., Kuhn, R., Susulic, V., Rex-Rabe, S., Yang, X., Zhou, X., Zhang, Y., Gillooly, K., Brosius, R., Ravishankar, R., Waggie, K., Mink, K., Price, L., Rehfuss, R.,

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.69 MB

english, 2014

22

A fibronectin scaffold approach to bispecific inhibitors of epidermal growth factor receptor and insulin-like growth factor-I receptor

Emanuel, Stuart L., Engle, Linda J., Chao, Ginger, Zhu, Rong-Rong, Cao, Carolyn, Lin, Zheng, Yamniuk, Aaron P., Hosbach, Jennifer, Brown, Jennifer, Fitzpatrick, Elizabeth, Gokemeijer, Jochem, Morin, P

Journal:

Year:

2011

Language:

english

File:

PDF, 3.02 MB

english, 2011

23

Role of Self-Association and Supersaturation in Oral Absorption of a Poorly Soluble Weakly Basic Drug

Narang, Ajit S., Badawy, Sherif, Ye, Qingmei, Patel, Dhaval, Vincent, Maria, Raghavan, Krishnaswamy, Huang, Yande, Yamniuk, Aaron, Vig, Balvinder, Crison, John, Derbin, George, Xu, Yan, Ramirez, Anton

Journal:

Pharmaceutical Research

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

24

The Interaction between Calcium- and Integrin-binding Protein 1 and the IIb Integrin Cytoplasmic Domain Involves a Novel C-terminal Displacement Mechanism

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 673 KB

english, 2006

25

Calcium-dependent and -independent Binding of Soybean Calmodulin Isoforms to the Calmodulin Binding Domain of Tobacco MAPK Phosphatase-1

Rainaldi, M., Yamniuk, A. P., Murase, T., Vogel, H. J.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.03 MB

english, 2006

26

Structurally Homologous Binding of Plant Calmodulin Isoforms to the Calmodulin-binding Domain of Vacuolar Calcium-ATPase

Yamniuk, A. P., Vogel, H. J.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 910 KB

english, 2004

27

Solution Structures of Ca2+-CIB1 and Mg2+-CIB1 and Their Interactions with the Platelet Integrin IIb Cytoplasmic Domain

Huang, H., Ishida, H., Yamniuk, A. P., Vogel, H. J.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 4.08 MB

english, 2011

28

The Solution Structures of Two Soybean Calmodulin Isoforms Provide a Structural Basis for Their Selective Target Activation Properties

Ishida, H., Huang, H., Yamniuk, A. P., Takaya, Y., Vogel, H. J.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 648 KB

english, 2008

29

The structure of the death receptor 4–TNF-related apoptosis-inducing ligand (DR4–TRAIL) complex

Ramamurthy, Vidhyashankar, Yamniuk, Aaron P., Lawrence, Eric J., Yong, Wei, Schneeweis, Lumelle A., Cheng, Lin, Murdock, Melissa, Corbett, Martin J., Doyle, Michael L., Sheriff, Steven

Journal:

Acta Crystallographica Section F Structural Biology Communications

Year:

2015

File:

PDF, 1.67 MB

2015

30

The structure of the death receptor 4–TNF-related apoptosis-inducing ligand (DR4–TRAIL) complex

Ramamurthy, Vidhyashankar, Yamniuk, Aaron P., Lawrence, Eric J., Yong, Wei, Schneeweis, Lumelle A., Cheng, Lin, Murdock, Melissa, Corbett, Martin J., Doyle, Michael L., Sheriff, Steven

Journal:

Acta Crystallographica Section F Structural Biology Communications

Year:

2015

Language:

english

File:

PDF, 1.67 MB

english, 2015

31

OR4 A case of heart valve replacement leading to extensive sensitization

Yamniuk, Christine, Campbell, Patricia, Wong, Jackson, Hidalgo, Luis

Journal:

Human Immunology

Year:

2015

Language:

english

File:

PDF, 688 KB

english, 2015

32

Characterization and quantification of histidine degradation in therapeutic protein formulations by size exclusion-hydrophilic interaction two dimensional-liquid chromatography with stable-isotope labeling mass spectrometry

Wang, Chunlei, Chen, Sike, Brailsford, John A., Yamniuk, Aaron P., Tymiak, Adrienne A., Zhang, Yingru

Journal:

Journal of Chromatography A

Year:

2015

Language:

english

File:

PDF, 628 KB

english, 2015

33

Calmodulin has the Potential to Function as a Ca 2+ -Dependent Adaptor Protein

Yamniuk, Aaron P., Rainaldi, Mario, Vogel, Hans J.

Journal:

Plant Signaling & Behavior

Year:

2007

Language:

english

File:

PDF, 562 KB

english, 2007

34

Functional antagonism of human CD40 achieved by targeting a unique species-specific epitope

Yamniuk, Aaron P., Suri, Anish, Krystek, Stanley R., Tamura, James, Ramamurthy, Vidhyashankar, Kuhn, Robert, Carroll, Karen, Fleener, Catherine, Ryseck, Rolf, Cheng, Lin, An, Yongmi, Drew, Philip, Gra

Journal:

Journal of Molecular Biology

Year:

2016

Language:

english

File:

PDF, 1.30 MB

english, 2016

35

Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement

Dahan, Rony, Barnhart, Bryan C., Li, Fubin, Yamniuk, Aaron P., Korman, Alan J., Ravetch, Jeffrey V.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.84 MB

english, 2016

36

Comparison of Ensemble and Single Molecule Methods for Particle Characterization and Binding Analysis of a PEGylated Single-Domain Antibody

Schneeweis, Lumelle A., Obenauer-Kutner, Linda, Kaur, Parminder, Yamniuk, Aaron P., Tamura, James, Jaffe, Neil, O’Mara, Brian W., Lindsay, Stuart, Doyle, Michael, Bryson, James

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 3.09 MB

english, 2015

37

BMS-986089 is a high affinity anti-myostatin adnectin that increases muscle volume in three preclinical species

Madireddi, M., Malone, H., Kukral, D., Chimalakonda, A., Kozhich, A., Xiling, Y., Swain, J., Yamniuk, A., Ahlijanian, M.

Journal:

Neuromuscular Disorders

Year:

2016

Language:

english

File:

PDF, 207 KB

english, 2016

38

P083 Tools of the trade: How antigen density stacks up on single antigen beads, a comparison of two vendors

Halpin, Anne, Hidalgo, Luis, Yamniuk, Christine, Manna, Deanna, Campbell, Patricia

Journal:

Human Immunology

Year:

2016

Language:

english

File:

PDF, 512 KB

english, 2016

39

Fc-Silent Anti-CD154 Domain Antibody Effectively Prevents Nonhuman Primate Renal Allograft Rejection

Kim, S. C., Wakwe, W., Higginbotham, L. B., Mathews, D. V., Breeden, C. P., Stephenson, A. C., Jenkins, J., Strobert, E., Price, K., Price, L., Kuhn, R., Wang, H., Yamniuk, A., Suchard, S., Farris, A.

Journal:

American Journal of Transplantation

Year:

2017

Language:

english

File:

PDF, 857 KB

english, 2017

40

Solution structures of the SH3 domains from Shank scaffold proteins and their interactions with Cav1.3 calcium channels

Ishida, Hiroaki, Skorobogatov, Anton, Yamniuk, Aaron P, Vogel, Hans J

Journal:

Year:

2018

Language:

english

File:

PDF, 1.23 MB

english, 2018

41

IL-2/CD25: A Long-Acting Fusion Protein That Promotes Immune Tolerance by Selectively Targeting the IL-2 Receptor on Regulatory T Cells

Ward, Natasha C., Yu, Aixin, Moro, Alejandro, Ban, Yuguang, Chen, Xi, Hsiung, Sunnie, Keegan, James, Arbanas, Jaren M., Loubeau, Martine, Thankappan, Anil, Yamniuk, Aaron P., Davis, Jonathan H., Strut

Journal:

The Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 2.62 MB

english, 2018

42

Bioavailability of protein therapeutics in rats following inhalation exposure: Relevance to occupational exposure limit calculations

Gould, Janet C., Carvajal, Irvith, Davidson, Todd, Graham, Jessica, Hillegass, Jedd, Julien, Susan, Kozhich, Alex, Wang, Bonnie, Wei, Hui, Yamniuk, Aaron P., Mathias, Neil, Haggerty, Helen G., Grazian

Journal:

Regulatory Toxicology and Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.29 MB

english, 2018

43

MIRG Survey 2011: Snapshot of Rapidly Evolving Label-Free Technologies Used for Characterizing Molecular Interactions

Yadav, Satya P., Bergqvist, Simon, Doyle, Michael L., Neubert, Thomas A., Yamniuk, Aaron P.

Journal:

Journal of Biomolecular Techniques JBT

Year:

2012

Language:

english

File:

PDF, 103 KB

english, 2012

44

Characterization of Mauritian Cynomolgus Macaque FcγR Alleles Using Long-Read Sequencing

Haj, Amelia K., Arbanas, Jaren M., Yamniuk, Aaron P., Karl, Julie A., Bussan, Hailey E., Drinkwater, Kenneth Y., Graham, Michael E., Ericsen, Adam J., Prall, Trent M., Moore, Kristina, Cheng, Lin, Gao

Journal:

The Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 1.50 MB

english, 2018

45

Development of a Model Protein Interaction Pair as a Benchmarking Tool for the Quantitative Analysis of 2-Site Protein-Protein Interactions

Yamniuk, Aaron P., Newitt, John A., Doyle, Michael L., Arisaka, Fumio, Giannetti, Anthony M., Hensley, Preston, Myszka, David G., Schwarz, Fred P., Thomson, James A., Eisenstein, Edward

Journal:

Journal of Biomolecular Techniques JBT

Year:

2015

File:

PDF, 4.59 MB

2015

46

ABRF–MIRG Benchmark Study: Molecular Interactions in a Three-Component System

Yamniuk, Aaron P., Edavettal, Suzanne C., Bergqvist, Simon, Yadav, Satya P., Doyle, Michael L., Calabrese, Kelly, Parsons, James F., Eisenstein, Edward

Journal:

Journal of Biomolecular Techniques JBT

Year:

2012

Language:

english

File:

PDF, 2.58 MB

english, 2012

47

Investigation of anomalous charge variant profile reveals discrete pH-dependent conformations and conformation-dependent charge states within the CDR3 loop of a therapeutic mAb

Lan, Wenkui, Valente, Joseph J., Ilott, Andrew, Chennamsetty, Naresh, Liu, Zhihua, Rizzo, Joseph M., Yamniuk, Aaron P., Qiu, Difei, Shackman, Holly M., Bolgar, Mark S.

Journal:

Year:

2020

File:

PDF, 2.76 MB

2020